AI-powered diagnostics

The Future of microscopy is here

SigTuple combines AI, robotics, microfluidics, and high-resolution microscopy to automate microscopic analysis of biological samples — across human and veterinary diagnostics.

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Our Products

Precision instruments for every diagnostic need

Three purpose-built platforms with use cases spanning point-of-care settings and clinical laboratories — each designed to assist pathologists and clinicians make timely accurate decisions.

AS76 — SigTuple edge AI digital morphology analyser
CE-IVDR Compliant
AS76

Medium and large laboratories

Next-generation automated AI powered digital cell morphology analyser for peripheral blood smear. Best-in-class image resolution with true 100X oil immersion. Scans 6 slides simultaneously with 200-cell leukocyte differential. All AI models run on the device, with no cloud dependency and complete data privacy.

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AI100 — SigTuple automated digital microscope
FDA + CE Cleared
AI100

Small and medium laboratories

World's only automated AI powered multi-purpose digital cell morphology analyser for both peripheral blood smear and urine sediment. 40X image resolution. AI aided remote review and unlimited scan storage on cloud.

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SigVet
Vet Diagnostics
SigVet

Point of care settings for veterinary clinics

Multi-test, AI-powered point-of-care platform for veterinary clinics, integrating microscopy, microfluidics and intelligent workflows to deliver reliable results across blood, urine and other biological samples.

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Core Technology

Four pillars of intelligent diagnostics

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Automated Digital Microscopy

Robotic optics & deep learning — 30+ cell types at pathologist-grade accuracy.

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Microfluidics & Biochemistry

Precision capillary-driven sample handling for lab-grade consistency at every step.

Edge AI Diagnostics

On-device inference — near real-time results with zero cloud dependency.

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Remote Review & Scale

Browser-based pathologist review from anywhere, at any scale.

Real-World Impact

Changing lives at the last mile

AI-powered microscopy is reaching patients in places where specialist pathologists never could. Here are three stories from the field.

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Rural Healthcare · Maharashtra

Early leukaemia detection in rural Maharashtra

AI-powered microscopy helped doctors in rural Maharashtra detect leukaemia early and begin treatment in time — in a region where specialist pathologists are scarce and manual review often delayed critical diagnoses.

Read on Livemint
Source: Livemint
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Diagnostics Access · India

Krsnaa Diagnostics scales quality care to rural India

Krsnaa Diagnostics leverages AI-powered microscopy to expand access to reliable, standardised diagnostics across rural India — replacing inconsistent manual review with automated, reproducible analysis at scale.

Read on Economic Times ↗
Source: Economic Times Health
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Tribal Healthcare · Tamil Nadu

AI-driven lab diagnostics in a tribal hospital, rural Tamil Nadu

A remote tribal hospital in Tamil Nadu uses AI-driven lab diagnostics to deliver microscopic testing to patients who previously had no access — turning a village health centre into a capable diagnostic unit overnight.

Read on BusinessLine ↗
Source: The Hindu BusinessLine
Partners & Customers

Trusted by global leaders

SigTuple customers and partners: Krsnad Diagnostics, Dr Lal PathLabs, Agilus Diagnostics, Vijaya Diagnostic Centre, HCG, Manipal Hospitals, Apollo Hospitals, HORIBA, THC Tawada Healthcare, Biomed Global, BJC, United MakGroup and many more
In the News

SigTuple in the media

Coverage, interviews and features from across the industry.

12 min read

SigTuple reinventing care

Startups are using the latest technologies to cure the health care system of its many chronic ailments, while putting the patient first

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14 min read

AI100 in Parbhani, Maharastra

AI saved a boy from leukaemia in rural Maharashtra—before it was too late

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2 min read

U.S. FDA approval for AI100 with Shonit

Medtech company Sigtuple receives U.S. FDA approval for its blood smear application. This innovative solution automates ...

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6 min read

Navigating the "biggest bottleneck"

Scientist Builds AI-Enabled Device to Help Diagnose Diseases in Under a Minute

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5 min read

CNBC-TV18 Startup Street's feature story

SigTuple along Krsnaa Diagnostics is leveraging AI to deliver quality diagnostics to rural India.

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2 min read

Health Tech 100

SigTuple has just been recognized as one of the top 100 health tech companies in South Asia.

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1 min read

HORIBA and SigTuple partnered up!

“AI100 added to HORIBA’s existing portfolio, enables a complete automation solution to be offered to all labs...

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2 min read

HCG hospitals adopts SigTuple AI100

HealthCare Global Enterprises Ltd (HCG) adopts artificial intelligence-powered to automate the manual microscopy (screening) process ..

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2 min read

Automated digital microscopy picks up!

As of today, there is one pathologist for a population of 65000 people

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3 min read

SigTuple can save lives - Medicircle

We have over 2.7 million cancer cases in our country. Each year we add 1.3 million new cases and we lose 8.5 lakh patients.

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7 min read

SigTuple Digital Microscopy-WIPO

An Indian company is automating microscopy in medical labs with an artificial intelligence-powered solution.

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4 min read

Building AI for Medical Applications

"First and foremost is the lack of qualified medical professionals. In India, the doctor-to-patient ratio is around 1:1700"

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2 min read

Screen blood samples in a minute

“It can detect all the types of blood cancers, all the types of anemiae, parasitic infections, malarial or viral and even cases of dengue,” he said

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2 min read

Quality healthcare in rural India

Healthtech startup SigTuple, has joined hands with Silicon Valley Bank (SVB) for the deployment of AI100,at a remote tribal hospital in Gudalur, TN.

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2 min read

AI drives lab tests in a rural hospital

A hospital in Tamil Nadu which treats adivasis is using a unique technology to help patients receive access to diagnostic reports within hours.

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1 min read

Microfluidics and AI Microscopy for Hb

Researchers at the Indian Institute of Science and SigTuple Technologies, a company based in Bengaluru, India, have developed ...

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2 min read

Startup Story: SigTuple

It all started when Tathagato Rai Dastidar lost his father almost two decades ago to misdiagnosis of acute myeloid leukaemia. This led him to quit his job and take the ...

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3 min read

RAISE 2020: AI in healthcare

Perseverance and persistence are the two words that best describes the spirit of Tathagato Rai Dastidar, Co-founder and CEO of SigTuple Technologies.

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5 min read

SigTuple CEO: “We will persevere..”

As with everything related to COVID-19 crisis, these unprecedented times have given rise to situations and events that would have otherwise been ...

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3 min read

Smarter disease diagnosis

A revolutionary breakthrough in artificial intelligence is that it allows machines to understand the scientific data and present results that could save lives. Selection ....

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2 min read

SigTuple: New investor in Series C round

Medical-technology startup SigTuple Technologies Pvt. Ltd on Tuesday said it has raised $16 million (Rs 111 crore) in a ....

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3 min read

SigTuple disrupting diagnostic space

With AI and machine learning overtaking every facet of millennial industry revolution, Healthcare AI application has far-reaching...

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1 min read

SigTuple awarded at Google's Demo Day

Bengaluru-based SigTuple was given the "Judges' Choice" award at the Google's first Demo Day Asia programme held in Shanghai

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2 min read

ET Startup's Top Innovator award

SigTuple won the 'Top Innovator' award at ET Startup Awards 2018. The core product of the company is Manthana–an AI-based platform.

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3 min read

SigTuple raises $19 Mn from Accel, IDG,.

Bengaluru-based start-up SigTuple raises $19 million in its Series B round led by Accel Partners and IDG Ventures

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3 min read

AI to Solve Pathologist Shortage

Ever since a Dutch cloth merchant accidentally discovered bacteria in 1676, microscopes have been a critical tool for medicine. Today’s microscopes are 800,000 ...

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8 min read

Top 5 AI startups for social impact

With so many deadly diseases out there, you need a lot of medical tests. SigTuple, an Indian startup, wants to use AI to dramatically improve the speed, accuracy, ...

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3 min read

India’s biggest funding in healthcare AI

The World Health Organization requires a pathologist to spend 20 minutes examining a blood smear on a slide under a microscope ...

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10 min read

AI: a life-saver for diagnostics

As a haematologist (physicians who specialise in the diagnosis, treatment and prevention of diseases related to blood), Dr Preethi Chari interprets art for a ...

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3 min read

SigTuple’s AI assistant to pathologist

Think matching pictures with words is child’s play? Not when those images are of blood samples and are being used to tell the ....

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2 min read

SigTuple raises seed fund

Bengaluru-based medical technology startup SigTuple, which was founded by former American Express executives, has received a round of seed investment ...

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FAQs

Common questions about AI diagnostics

Answers to the questions we hear most often from laboratory teams and clinicians exploring AI-powered microscopy.

AI-powered microscopy combines digital imaging with artificial intelligence to assist in the analysis of microscopic samples. Instead of relying solely on manual examination, AI helps identify, classify, and prioritize findings, enabling laboratories to review samples more efficiently and consistently. By bringing together microscopy, digital workflows, and intelligent analysis, AI-powered microscopy helps laboratories handle growing diagnostic workloads while maintaining quality and accuracy. In veterinary settings, AI-powered microscopy can also help bring laboratory-grade diagnostic capabilities closer to the point of care, enabling veterinary clinics to access the accuracy and insights traditionally available only through specialized diagnostic laboratories.

Digital pathology transforms traditional glass slides into high-resolution digital images that can be viewed, analyzed, and shared electronically. Once digitized, slides can be reviewed on a computer, stored securely, and accessed by pathologists from different locations. Digital pathology streamlines collaboration, supports remote consultations, and creates opportunities for AI-assisted analysis, helping laboratories improve efficiency and access to specialist expertise.

Automated smear review uses digital imaging and AI-assisted analysis to evaluate peripheral blood smears and highlight clinically relevant findings for further review. Rather than replacing laboratory professionals, automated smear review helps prioritize cases, reduce repetitive manual tasks, and support more consistent morphology assessment. This enables laboratories to manage increasing sample volumes while maintaining confidence in diagnostic workflows.

AI helps improve laboratory workflows by automating time-consuming review steps, assisting with morphology analysis, and providing decision support during sample evaluation. By reducing manual effort and helping standardize reviews, AI enables laboratory teams to process samples more efficiently and focus their expertise where it matters most. The result is a more streamlined pathology workflow that supports faster reporting, greater consistency, and improved scalability.

Yes. One of the key advantages of digital pathology is the ability to securely access and review digital slides from virtually anywhere. This enables remote pathology review, making it easier for laboratories to collaborate with specialists, obtain second opinions, and extend diagnostic services to locations where expertise may not be readily available. Remote review can help improve turnaround times while expanding access to quality diagnostics.

SigTuple helps laboratories scale by combining AI-powered microscopy, digital pathology workflows, and automation technologies into a unified diagnostic platform. By reducing dependence on manual processes and enabling efficient review workflows, SigTuple supports higher sample volumes without a proportional increase in workload. This allows laboratories to grow their diagnostic capacity while maintaining consistency, quality, and operational efficiency.

SigTuple platforms are designed to support a wide range of diagnostic environments, including independent laboratories, hospital laboratories, pathology centers, reference laboratories, and veterinary diagnostic facilities. Whether the goal is to modernize microscopy workflows, enable digital pathology adoption, improve hematology operations, or expand access to specialist review, SigTuple solutions can be adapted to the needs of laboratories of different sizes and testing volumes.

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